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Bombesin-like receptor 3 : ウィキペディア英語版 | Bombesin-like receptor 3
The bombesin receptor subtype 3 also known as BRS-3 or BB3 is a protein which in humans is encoded by the ''BRS3'' gene. == Function ==
Mammalian bombesin-like peptides are widely distributed in the central nervous system as well as in the gastrointestinal tract, where they modulate smooth-muscle contraction, exocrine and endocrine processes, metabolism, and behavior. They bind to G protein-coupled receptors on the cell surface to elicit their effects. Bombesin-like peptide receptors include gastrin-releasing peptide receptor, neuromedin B receptor, and bombesin-like receptor-3 (BRS3; this article).〔〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=680 )〕 BB3 is a G protein-coupled receptor.〔 BB3 only interacts with known naturally-occurring bombesin-related peptides with low affinity and therefore, as it has no natural high-affinity ligand, is classified as an orphan receptor.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Bombesin-like receptor 3」の詳細全文を読む
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